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KMID : 0363220170550020110
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Korean Journal of Dermatology
2017 Volume.55 No. 2 p.110 ~ p.115
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Characteristics of Atopic Dermatitis in a Post-childhood Atopic March Group
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Lee He-Min
Shin Jung-U
Lee Jung-Soo
Chu Howard
Lee Kwang-Hoon
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Abstract
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Background: Little knowledge is available on the characteristic differences between patients with atopic dermatitis (AD) with and without atopic march after childhood.
Objective: To observe and compare the phenotypes of patients with AD in regards to atopic march tendency at a single point.
Methods: We enrolled patients with AD aged between 10 and 30 years. The patients were divided into the atopic march and non-atopic march groups on the basis of an investigator-designed survey questionnaire, and their serum-specific immunoglobulin E (IgE) levels or results of the skin prick test were compared.
Results: In a total of 182 patients enrolled in the study, 93 patients with atopic march and 89 patients with non-atopic march were observed. When their serum-specific IgE levels or results of the skin prick test were compared between the two groups, there was no significant difference, except for a in the atopic march group. Analysis of AD severity, family history of allergic diseases, and total IgE levels between the two groups showed no statistically significant differences.
Conclusion: Our findings suggest that although no apparent phenotype characteristics could differentiate the presence of atopic march, the history of the patient`s allergic diseases should be revalidated, and clinicians should watch out for future developments of atopic march when a patient shows a high-class sensitization rate to dust mite.
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KEYWORD
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Atopic dermatitis, Atopic march, Allergic march, Dust mite
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